How Do Nitrates Relax Smooth Muscle In Treatment For Angina, How Do Nitrates Relax And Widen Blood Vessels To Allow More Blood Flow To The Heart?

In treatment for angina, how do nitrates relax and widen blood vessels to allow more blood flow to the heart? - how do nitrates relax smooth muscle

Nitrate Act by relaxing the smooth muscles. Increases the formation of cGMP, as the basis of their cellular effects. Press nitrate, nitric oxide, which activates a cytosolic form of soluble guanylate cyclase in vascular smooth muscle by interacting with the heme of the enzyme. increases the formation of cGMP ultimately leads to the relaxation of smooth muscles, ie the expansion of the vessel.